The Tolan Center for Healthcare Speaker Series: A Conversation with Novartis CEO Vas Narasimhan

Vas Narasimhan

Vas Narasimhan Discusses Leadership and AI in Healthcare

The Novartis CEO joined Booth’s Ream Qato for a conversation with students about his career path, the future of pharmaceutical innovation, and mission-driven leadership.

Vas Narasimhan, AB’98, CEO of Novartis, and Ream Qato, MBA ’15, Booth Adjunct Assistant Professor of Healthcare Management, shared an engaging conversation with students at a recent event hosted by the Tolan Center for Healthcare on February 26, 2026. A packed audience of MBA and other students listened as he shared his story, beginning with his training as a physician seeking to make an impact at scale, through his “accidental CEO” journey, resulting in a complex cultural and business transformation of Novartis into a pure-play industry leader. 

Audience asking questions during Tolan Center Speaker series.

When asked about the future of AI in the industry, Vas described opportunities over short and longer-term horizons. He offered a grounded view of AI’s role in healthcare, noting that while near-term disruption in key industry benchmarks may be modest, long-term gains could meaningfully accelerate the industry, including reducing the timeline from early discovery to patients, or increasing the probability of success for new medicines.

Some of our favorite advice Vas shared with MBA students:

  • Embrace a broad career early on, with lateral moves to get experience. As humans, we’re not great at predicting what the world will look like in the future, but diverse experiences build comfort with being curious and allow you to adapt.
  • Develop the ability to communicate with different audiences as a leader (e.g. scientists, financial analysts, politicians, and media).
  • The hardest thing as a leader is learning when not to disregard the margin idea. You have to listen, trust your experts, and triage effectively. Most of the time, you’ll say “no”, but a few of these ideas might make a significant difference for both patients and the business.

Vas brings a distinctive perspective among leaders of major life sciences firms, drawing on his background as a medical doctor who rose through R&D to the CEO chair. He chairs the Novartis innovation board himself, pushing for fundamental advances in science. When asked about balancing humanitarian versus business interests in drug development, Vas emphasized mission-driven leadership: he’s in the business of reimagining medicine to deliver the best possible options for patients, not simply selling drugs.

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